CELL DELIVERY SYSTEM AND METHOD
The present invention is directed to a cell delivery system for the delivery of materials including nucleic acids across a biological barrier and methods of use thereof. The cell delivery system of the invention comprises a microprotrusion array composed of a swellable and/or dissolvable polymer composition for use in the transport of a material across a biological barrier, wherein the material comprises nanoparticles formed from a nucleic acid complexed with an amphipathic cell penetrating peptide and wherein the microprotrusion array is loaded with the nanoparticles.
» Number: US2017112760A1 (A1)
» Publication Date: 27/04/2017
» Applicant: THE QUEEN'S UNIV OF BELFAST?[GB]
» Inventor: MCCARTHY HELEN?[GB]; DONNELLY RYAN?[GB] (1)
This project has received funding from the European Union's Horizon 2020 research and innovation programme under grant agreement Nº 768737